Understanding the Complex Biology and Progression of HIV/AIDS
HIV/AIDS remains one of the most complex and deeply studied diseases in modern medical science. To better understand its origins, progression, and impact on the immune system, this series explores key aspects of the virus from both a clinical and molecular perspective. Each section provides focused insights into specific elements of HIV biology, immune dysfunction, and the broader implications for disease development.
The following topics are covered in depth across individual pages, each linked for easy reference:
- AIDS Statistics and Background of the Problem
- Background of the Science
- Periods of Immune Dysfunction, Viral Propagation, and Transition to Clinical AIDS
- The Initial Viral Infection and Lack of a Vigorous Pro-Inflammatory Response Against the Virus
- The Relative Absence of Tumor Necrosis Factor During the Primary Immune Response
- The Excessive Presence of TGFβ During the Primary Immune Response Against HIV
- The Enhancing Effects of Physiological and Psychological Stress on HIV Infectivity
- The Induction of Immunosuppression by HIV Viral Particles
- The Biology of NEF
- The Biology of VPR
- The Biology of TAT
- HIV-Induced Autoimmunity
- Conclusion
Each page aims to build a clearer picture of how HIV undermines immune function, manipulates cellular processes, and persists despite the body’s defenses. The series concludes with a summary of findings and reflections on the biological challenges shaping HIV/AIDS research.